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Biologist
Biologist
发布于 大约 7 小时前普通员工/个人贡献者
Cambridge, Massachusetts
高级经验
全职员工
仅现场办公
博士
研究与开发 (研发)
Cro Management
Immuno-Oncology
Small Molecules
Cancer Biology
Preclinical Development
Protacs
Target Discovery
Translational Biomarker
AI 估算 · 70k–110k
Based on senior level in oncology, high demand skills, and large biopharma in Cambridge, MA. Market data for similar roles.
职位详情
关于这个职位
This Biologist role at Sanofi leads oncology and immuno-oncology drug discovery programs from target identification to preclinical proof-of-concept. You will combine strategic project leadership with hands-on lab work, leveraging deep expertise in cancer biology and translational science. The position offers the chance to shape early discovery programs and collaborate extensively with internal and external partners in a cutting-edge, AI-powered R&D environment.
最低要求
PhD (or equivalent) in cancer biology, immunology, molecular biology, or a related life sciences discipline.
Postdoctoral and industry experience in cancer biology and/or immuno-oncology research.
Strong track record in target identification and validation, mechanism-of-action studies, and biomarker discovery.
Demonstrated experience supporting preclinical development of oncology therapeutics.
Highly familiar with multiple therapeutic modalities, including small molecules, degraders (e.g., PROTACs), and biologics.
Proven ability to lead scientific projects while contributing experimentally when required.
Experience managing external research collaborations with CROs and academic or industry partners.
Excellent scientific communication skills.
Experience working with large scale data mining, or target discovery and translation to patient.
工作职责
Lead and drive oncology and immuno-oncology discovery programs, from target identification through preclinical proof-of-concept.
Contribute deep expertise in cancer biology, tumor immunology, and translational science, informing target selection, indication strategy, and experimental design.
Support the discovery and preclinical development of innovative cancer therapeutics using diverse modalities, including small-molecule inhibitors, targeted degraders, and biologics.
Provide scientific leadership while remaining capable of hands-on laboratory work, as needed, to directly support project teams.
Manage and coordinate external collaborations with CROs, academic groups, and industry partners, ensuring scientific rigor, alignment with project goals, and timely delivery.
优先资格
Prior experience advancing programs from target-ID to development candidate.
Publications and/or patents in oncology or immuno-oncology research.
Experience working in a matrixed, cross-functional pharmaceutical research environment.
AI 洞察
优缺点分析
优点
- Work on cutting-edge oncology therapeutics with diverse modalities, gaining broad expertise.
- Join a top-tier biopharma company with strong R&D investment and AI-powered platforms.
- Opportunity to shape early discovery and impact pipeline decisions.
- Excellent benefits and career development programs in a global organization.
- High expectations for both strategic leadership and hands-on lab work, demanding versatility.
- Fast-paced, competitive field with pressure to deliver proof-of-concept results.
- Requires managing multiple external collaborations, which can be logistically complex.
- This role is ideal for an experienced cancer biologist who enjoys both leading projects and working at the bench, and thrives in a collaborative, innovative environment.
缺点 / 挑战
暂无明显挑战项
角色解读
- Progress to Senior Scientist or Principal Scientist, leading larger discovery programs.
- Move into higher-level strategic roles such as Head of Discovery or Translational Science.
- Opportunities to transition into biomarker or precision medicine leadership within R&D.
- Lead early-stage oncology and immuno-oncology drug discovery projects from target identification to preclinical proof-of-concept.
- Design and execute experiments to validate targets, study mechanisms of action, and develop translational biomarkers.
- Coordinate external collaborations with CROs and academic partners to advance pipeline programs.
- Contribute to strategic decisions on target selection, indication strategy, and therapeutic modality choice.
- Deep expertise in cancer biology, immunology, and translational science.
- Hands-on experience with various therapeutic modalities: small molecules, PROTACs, and biologics.
- Strong project leadership and ability to work both strategically and experimentally.
- Excellent communication and collaboration skills for managing cross-functional and external partnerships.
申请策略
- Tailor your cover letter to show how your expertise aligns with Sanofi's mission and pipeline.
- Highlight any experience with degraders (PROTACs) as a differentiator.
- Emphasize track record in target identification and validation with specific examples and impact.
- Highlight experience with multiple therapeutic modalities (small molecules, PROTACs, biologics).
- Showcase project leadership and ability to manage external collaborations.
- Include publications, patents, or presentations in oncology/immuno-oncology.
- Familiarize with AI/ML tools for drug discovery, as Sanofi emphasizes AI-powered research.
- Deepen understanding of translational biomarker strategies and clinical correlations.
面试指南
- Use the STAR method (Situation, Task, Action, Result) for behavioral questions.
- For technical questions, demonstrate deep mechanistic understanding and connect to broader strategy.
- Show enthusiasm for collaboration and innovation, aligning with Sanofi's culture.
- Describe a time you led a target discovery project from idea to validation. What challenges did you face?
- How do you approach selecting the right therapeutic modality for a given target?
- Explain a translational biomarker strategy you implemented in a preclinical program.
- How do you manage multiple external collaborations to ensure scientific quality and timely delivery?
- What is your experience with PROTACs or targeted degraders, and how do you compare them to traditional small molecules?
职位点评
71
综合评分
High-impact oncology discovery role at a top biopharma, offering cutting-edge science and growth but requiring onsite presence and likely high intensity.
更适合这类人
This role is best suited for a scientist who prioritizes meaningful impact and career growth over work-life balance and flexible arrangements.
表现最好
使命价值
相对薄弱
工作生活
薪资福利70
成长发展85
工作生活40
使命价值90
薪资福利
70中等
The position offers competitive compensation typical of senior roles at large biopharma in Cambridge, but exact figures are not disclosed. Benefits are comprehensive, including healthcare and parental leave.
薪资信号未披露（AI估算：70K-110K/月）
福利待遇high-quality healthcare、prevention and wellness programs、at least 14 weeks’ gender-neutral parental leave
成长发展
85较高
Strong growth opportunities through leading edge projects, diverse modalities, and company's investment in AI and data. Career development programs and potential for lateral or promotional moves are explicitly mentioned.
技术前沿前沿/新兴技术
技术栈oncology、immuno-oncology、AI、PROTACs、biologics、small molecules
成长机会opportunities to grow your talent、drive your career、promotion or lateral move
业务类型profit_center
工作生活
40较低
Onsite requirement in Cambridge, MA, with no indication of remote flexibility. The role involves hands-on lab work and likely high intensity. Work-life balance not explicitly addressed.
工作模式仅现场办公
办公地点市区核心地段
加班情况未提及（无法判断）
使命价值
90较高
High social impact through developing cancer therapies that could improve millions of lives. Company mission emphasizes 'chasing the miracles of science' and patient-centricity.
行业发展高速增长赛道
社会影响正向社会影响力较高
使命信号improve people's lives、chase the miracles of science、treat and protect millions
创新程度积极采用新技术
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